Publications

2025

  • Akash Mishra, Serdar Akkol, Elizabeth Espinal, Noah Markowitz, Gelana Tostaeva, Elisabeth Freund, Ashesh D. Mehta, Stephan Bickel. Hippocampal sharp wave ripples and coincident cortical ripples orchestrate human semantic networks. bioRxiv. PDF. Accepted for publication in iScience.
  • K. L. Christison-Lagay et al. The neural activity of auditory conscious perception. NeuroImage 308, 121041 (2025).
  • M. Keshishian et al. Parallel hierarchical encoding of linguistic representations in the human auditory cortex and recurrent automatic speech recognition systems. bioRxiv.
  • Sabina Gherman, Marcin Leczinski, Stephan Bickel. Intracranial EEG. Cognitive Neuroscience Methods. Springer Nature. Book Chapter (2025). In press.

2024

  • Akash Mishra, Gelana Tostaeva, Maximilian Nentwich, Elizabeth Espinal, Noah Markowitz, Sabina Gherman, Jalen Winfield, Ashesh D. Mehta, Stephan Bickel. Motifs of human hippocampal and cortical high frequency oscillations structure processing and memory of naturalistic stimuli. bioRxiv. PDF.
  • Vishal Choudhari, Cong Han, Stephan Bickel, Ashesh D. Mehta, Catherine Schevon, Guy M. McKhann, Nima Mesgarani. Brain-Controlled Augmented Hearing for Spatially Moving Conversations in Multi-Talker Environments. Adv. Sci. 11, 2401379 (2024) PDF.
  • Maximilian Nentwich, Marcin Leszczynski, Charles E Schroeder, Stephan Bickel, Lucas C Parra. Intrinsic dynamic shapes responses to external stimulation in the human brain. bioRxiv. PDF.
  • Akash Mishra, Serdar Akkol, Elizabeth Espinal, Noah Markowitz, Gelana Tostaeva, Elisabeth Freund, Ashesh D. Mehta, Stephan Bickel. Hippocampal sharp wave ripples and coincident cortical ripples orchestrate human semantic networks. bioRxiv. PDF.
  • Sabina Gherman, Noah Markowitz, Gelana Tostaeva, Elizabeth Espinal, Ashesh D. Mehta, Redmond G. O’Connell, Simon P. Kelly, Stephan Bickel. Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions. Nat Hum Beh. 8, 758–770 (2024).
  • V. S. Raghavan et al. Improving auditory attention decoding by classifying intracranial responses to glimpsed and masked acoustic events. Imaging Neurosci. 2, 1–19 (2024).
  • Kiki van der Heijden, Prachi Patel, Stephan Bickel, Jose L. Herrero, Ashesh D. Mehta, Nima Mesgarani. Joint population coding and temporal coherence link an attended talker’s voice and location features in naturalistic multi-talker scenes. bioRxiv. PDF.
  • Ruxue Gong, Stephan Bickel, Gelana Tostaeva, Fred A. Lado, Ashesh D. Metha, Ruben I. Kuzniecky, Leonardo F. Bonilha, Ezequiel L. Gleichgerrcht. Optimizing Surgical Planning for Epilepsy Patients With Multimodal Neuroimaging and Neurophysiology Integration: A Case Study. J. Clin. Neurophysiol. 41, 317–321 (2024).

2023

  • Gavin Mischler, Menoua Keshishian, Stephan Bickel, Ashesh D. Mehta, Nima Mesgarani. Deep neural networks effectively model neural adaptation to changing background noise and suggest nonlinear noise filtering methods in auditory cortex. NeuroImage. 266, 119819 (2023). PDF.
  • Vinay S Raghavan, James O’Sullivan, Stephan Bickel, Ashesh D Mehta, Nima Mesgarani. Distinct neural encoding of glimpsed and masked speech in multitalker situations. PLOS Biology 21, e3002128 (2023). PDF.
  • Sabina Gherman, Noah Markowitz, Gelana Tostaeva, Elizabeth Espinal, Ashesh D. Mehta, Redmond G. O’Connell, Simon P. Kelly, Stephan Bickel. Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions. bioRxiv. PDF.
  • Menoua Keshishian, Serdar Akkol, Jose Herrero, Stephan Bickel, Ashesh D. Mehta, Nima Mesgarani. Joint, distributed and hierarchically organized encoding of linguistic features in the human auditory cortex. Nat. Hum. Behav. 7, 740–753 (2023).
  • Marcin Leszczynski, Stephan Bickel, Maximilian Nentwich, Brian E. Russ, Lucas Parra, Peter Lakatos, Ashesh Mehta, Charles E. Schroeder. Saccadic modulation of neural excitability in auditory areas of the neocortex. Curr Biol 33, 1185-1195.e6 (2023).
  • Maximilian Nentwich, Marcin Leszczynski, Brian E. Russ, Lukas Hirsch, Noah Markowitz, Kaustubh Sapru, Charles E. Schroeder, Ashesh D. Mehta, Stephan Bickel, Lucas C. Parra. Semantic novelty modulates neural responses to visual change across the human brain. Nat Commun 14, 2910 (2023).

2022

  • Sam A Neymotin, Idan Tal, Annamaria Barczak, Monica N O’Connell, Tammy McGinnis, Noah Markowitz, Elizabeth Espinal, Erica Griffith, Haroon Anwar, Salvador Dura-Bernal, Charles E Schroeder, William W Lytton, Stephanie R Jones, Stephan Bickel, Peter Lakatos. Detecting spontaneous neural oscillation events in primate auditory cortex. Eneuro. ENEURO.0281-21.2022 (2022).
  • Prachi Patel, Bahar Khalijhinejad, Jose L. Herrero, Stephan Bickel, Ashesh D. Mehta, Nima Mesgarani. Improved Speech Hearing in Noise with Invasive Electrical Brain Stimulation. J. Neurosci. 42, 3648–3658 (2022).
  • Prachi Patel, Kiki van der Heijden, Stephan Bickel, Jose L. Herrero, Ashesh D. Mehta, Nima Mesgarani. Interaction of bottom-up and top-down neural mechanisms in spatial multi-talker speech perception. Curr Biol 32, 3971-3986.e4 (2022). PDF.
  • Arish Alreja et al. A new paradigm for investigating real-world social behavior and its neural underpinnings. Behav Res Methods 1–20 (2022).
  • Marcin Leszczynski, Stephan Bickel, Maximilian Nentwich, Brian E. Russ, Lucas Parra, Peter Lakatos, Ashesh Mehta, Charles E. Schroeder. Saccadic modulation of neural excitability in auditory areas of the neocortex. bioRxiv.

2021

  • Jose L. Herrero, Alexander Smith, Akash Mishra, Noah Markowitz, Ashesh D. Mehta, Stephan Bickel. Inducing neuroplasticity through intracranial θ-burst stimulation in the human sensorimotor cortex. J Neurophysiol. 126, 1723–1739 (2021). PDF.
  • Chad Bouton, Nikunj Bhagat, Santosh Chandrasekaran, Jose Herrero, Noah Markowitz, Elizabeth Espinal, Joo-won Kim, Richard Ramdeo, Junqian Xu, Matthew F. Glasser, Stephan Bickel, Ashesh Mehta. Decoding Neural Activity in Sulcal and White Matter Areas of the Brain to Accurately Predict Individual Finger Movement and Tactile Stimuli of the Human Hand. Front Neurosci 15, 699631 (2021).
  • Santosh Chandrasekaran*, Stephan Bickel*, (*equal contribution) Jose L. Herrero, Joo-won Kim, Noah Markowitz, Elizabeth Espinal, Nikunj A. Bhagat, Richard Ramdeo, Junqian Xu, Matthew F. Glasser, Chad E. Bouton, Ashesh D. Mehta. Evoking highly focal percepts in the fingertips through targeted stimulation of sulcal regions of the brain for sensory restoration. Brain Stimul 14, 1184–1196 (2021). PDF.
  • Bahar Khalighinejad, Prachi Patel, Jose L. Herrero, Stephan Bickel, Ashesh D. Mehta, Nima Mesgarani. Functional characterization of human Heschl’s gyrus in response to natural speech. Neuroimage 235, 118003 (2021). PDF.
  • Santosh Chandrasekaran, Matthew Fifer, Stephan Bickel, Luke Osborn, Jose Herrero, Breanne Christie, Junqian Xu, Rory K. J. Murphy, Sandeep Singh, Matthew F. Glasser, Jennifer L. Collinger, Robert Gaunt, Ashesh D. Mehta, Andrew Schwartz, Chad E. Bouton. Historical perspectives, challenges, and future directions of implantable brain-computer interfaces for sensorimotor applications. Bioelectron. Med. 7, 14 (2021). PDF.
  • Samuel A Neymotin, Idan Tal, Annamaria Barczak, Monica N. O’Connell, Tammy McGinnis, Noah Markowitz, Elizabeth Espinal, Erica Griffith, Haroon Anwar, Salvador Dura-Bernal, Charles E Schroeder, William W Lytton, Stephanie R Jones, Stephan Bickel, Peter Lakatos. Taxonomy of neural oscillation events in primate auditory cortex. Biorxiv 2020.04.16.045021 (2021).
  • Datta-Chaudhuri, T. et al. The Fourth Bioelectronic Medicine Summit “Technology Targeting Molecular Mechanisms”: current progress, challenges, and charting the future. Bioelectron. Med. 7, 7 (2021).

2020

  • Shihab Shamma, Prachi Patel, Shoutik Mukherjee, Guilhem Marion, Bahar Khalighinejad, Cong Han, Jose Herrero, Stephan Bickel, Ashesh Mehta, Nima Mesgarani. Learning Speech Production and Perception through Sensorimotor Interactions. Cereb Cortex Commun 2, tgaa091 (2020).
  • Idan Tal, Samuel Neymotin, Stephan Bickel, Peter Lakatos, Charles E. Schroeder. Oscillatory Bursting as a Mechanism for Temporal Coupling and Information Coding. Front Comput Neurosc 14, 82 (2020).
  • Westover MB et al. Diagnostic Value of Electroencephalography with Ten Electrodes in Critically Ill Patients. Neurocrit Care 1–12 (2020).

2019

  • Holdgraf, C. et al. iEEG-BIDS, extending the Brain Imaging Data Structure specification to human intracranial electrophysiology. Sci Data 6, 102 (2019).
  • Bickel S, Parvizi J. Electrical stimulation of the human claustrum. Epilepsy Behav 97, 296–303 (2019).

2018

  • Kucyi A et al. Intracranial Electrophysiology Reveals Reproducible Intrinsic Functional Connectivity within Human Brain Networks. J Neurosci 38, 4230-4242 (2018).
  • Benjamin CFA et al. Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning. Hum Brain Mapp 39, 2777–2785 (2018).
  • Benjamin CFA et al. Presurgical language fMRI: Technical practices in epilepsy surgical planning. Hum Brain Mapp 39, 4032–4042 (2018).

2017

  • Mégevand P, Groppe DM, Bickel S, Mercier MR, Goldfinger MS, Keller CJ, Entz L, Mehta AD. The Hippocampus and Amygdala Are Integrators of Neocortical Influence: A Cortico-Cortical Evoked Potential Study. Brain Connect. 7(10):648-660 (2017).
  • Shine JM, Kucyi A, Foster BL, Bickel S, Wang D, Liu H, Poldrack RA, Hsieh LT, Hsiang JC, Parvizi J. Distinct Patterns of Temporal and Directional Connectivity among Intrinsic Networks in the Human Brain. J Neurosci. 37(40):9667-9674 (2017).
  • Nariai H, Beal J, Galanopoulou AS, Mowrey WB, Bickel S, Sogawa Y, et al. Scalp EEG Ictal gamma and beta activity during infantile spasms: Evidence of focality. Epilepsia 51(Suppl. 1):2175 (2017).
  • Groppe DM, Bickel S, Dykstra AR, Wang X, Mégevand P, Mercier MR, Lado FA, Mehta AD, Honey CJ. iELVis: An open source MATLAB toolbox for localizing and visualizing human intracranial electrode data. J Neurosci Methods. (2017).

2016

  • Mercier MR, Bickel S, et al. Evaluation of cortical Local Field Potential diffusion in Stereotactic Electro-EncephaloGraphy recordings: a glimpse on white matter signal. Neuroimage 147, (2016).
  • Kuceyeski A, et al. The application of a mathematical model linking structural and functional connectomes in severe brain injury. Neuroimage Clin 11, 635-647 (2016).

2015

  • Martínez A, Gaspar PA, Hillyard SA, Bickel S, Lakatos P, Dias EC, Javitt DC. Neural oscillatory deficits in schizophrenia predict behavioral and neurocognitive impairments. Front Hum Neurosci. 9, 371 (2015).
  • Podvalny, E. et al. A unifying principle underlying the extracellular field potential spectral responses in the human cortex. J Neurophysiol 114, 505–519 (2015).
  • Noy, N. et al. Ignition’s glow: Ultra-fast spread of global cortical activity accompanying local “ignitions” in visual cortex during conscious visual perception. Conscious Cogn 35, 206-224 (2015).
  • Noy, N. et al. Intracranial recordings reveal transient response dynamics during information maintenance in human cerebral cortex. Hum Brain Mapp 36, 3988-4003 (2015).

2014

  • Keller, CJ et al. Corticocortical Evoked Potentials Reveal Projectors and Integrators in Human Brain Networks. J Neurosci 34, 9152-9163 (2014).
  • Entz L, Tóth E, Keller CJ, Bickel S, Groppe DM, Fabó D, Kozák LR, Bognár L, Wittner L, Erőss L, Ulbert I, Mehta AD. Evoked effective connectivity of the human neocortex. Hum Brain Mapp 35, 5736-5753 (2014).
  • Davidesco I, Zion-Golumbic E, Bickel S, Harel M, Groppe DM, Keller CJ, Schevon CA, McKhann G, Schroeder CE, Mehta AD. Exemplar Selectivity Reflects Perceptual Similarities in the Human Fusiform Cortex. Cereb Cortex 24, 1879–1893 (2014).

2013

  • Zion Golumbic, E. M., Ding N, Bickel S. et al. Mechanisms Underlying Selective Neuronal Tracking of Attended Speech at a “Cocktail Party.” Neuron 77, 980 991 (2013).
  • Keller, C., Bickel S. et al. Neurophysiological Investigation of Spontaneous Correlated and Anticorrelated Fluctuations of the BOLD Signal. J Neurosci 33, 6333 6342 (2013).
  • Dias EC, Bickel S, Epstein M, Sehatpour P, Javitt DC. Abnormal Task Modulation of Oscillatory Neural Activity in Schizophrenia. Frontiers in Psychol. 27;4:540 (2013).
  • Groppe DM, Bickel S, Keller CJ, Jain SK, Hwang ST, Harden C, Mehta AD. Dominant frequencies of resting human brain activity as measured by the electrocorticogram. Neuroimage 79:223-33 (2013).

Previous Years

  • Martínez A, Hillyard SA, Bickel S, Dias EC, Butler PD, Javitt DC. Consequences of magnocellular dysfunction on processing attended information in schizophrenia. Cereb Cortex 22(6):1282-93 (2012).
  • Bickel S, Dias EC, Epstein ML, Javitt DC. Expectancy-related modulations of neural oscillations in continuous performance tasks. Neuroimage 62(3):1867-76 (2012).
  • Keller, C.*, Bickel S.* (*equal contribution) et al. Intrinsic functional architecture predicts electrically evoked responses in the human brain. Proc National Acad Sci 108, 10308 10313 (2011).
  • Kantrowitz JT, Oakman E, Bickel S, Spielman A, Silipo G, Battaglia J, Citrome L, Javitt DC. The Importance of a Good Night’s Sleep: An Open-Label Trial of Sodium Oxybate (GHB) in Insomnia Associated with Schizophrenia. Schizophrenia Research 120(1-3):225-6 (2010).
  • Bickel S, Javitt DC. Neurophysiological and Neurochemical Animal Models of Schizophrenia: Focus on Glutamate. Beh. Brain Res. 204(2):352-6 (2009). Review article.
  • Nedeltchev K, Bickel S, Baumgartner RW. R2-recanalization of spontaneous carotid artery dissection. Stroke 40(2):499-504 (2009).
  • Bickel S, Lipp HP, Umbricht D. Early auditory sensory processing deficits in mouse mutants with reduced NMDA receptor function. Neuropsychopharmacology 33:1680-1689 (2008).
  • Bickel S, Lipp HP, Umbricht D. Impaired Attentional Modulation of Auditory Evoked Potentials in NMDA NR1 hypomorphic Mice. Genes Brain Behav 6:558-568 (2007).